The wafer processing apparatus includes a chamber that is pressurized to a pressure that is higher than the pressure of the exterior thereof, an opening portion through which the interior and the exterior of the chamber are in communication with each other, and a door that closes the opening portion. This disclosure also encompasses homologues of the edr3 gene from mammals, in particular from humans. Each ridge defined by first and second sidewalls, each sidewall having a first and second end. This device requires no external power, amplification, analog-to-digital conversion, software or hardware. The methods currently in use do not allow to monitor partial discharge activities in an apparatus in DC, because they do not allow to distinguish the signals relating to the partial discharges from those relating to noise or to disturbances. The nucleotide sequence of the target genes can be used for various drug discovery purposes, such as expression of the recombinant protein, hybridization assay and construction of nucleic acid arrays.