Systems and methods are disclosed for matching of individuals to one another using a matching model. A preferred treatment regime comprises administering greater than 10 mgkg body weight per week to a patient. The locking member includes a flange that is movable between a locking position wherein the flange holds the lock in the assembly and a release position wherein the flange permits the lock to be removed from the assembly. Likewise, the present invention requires only one mounting hole in the handle riser to minimize the negative structural ramifications of drilling multiple holes. The changes in reservoir fluid paths associated with the injection of an EOR agent are detected in the observation well.