A stretcher fiber includes a core region, inner trench region, ring region, outer trench region, and outer cladding region. In one aspect of the invention, a trimming method includes assembling one or more components of an electrical circuit onto a printed circuit board having one or more electrical connections coupled to the said one or more components. It is more for use on a soft cap with a stiff visor or brim than a hard hat. The semiconductor layer of a TFT sensor is formed to be aligned with a gate electrode when viewed from the upper side. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions.