Compounds useful for treating cellular proliferative diseases and disorders by inhibiting the activity of KSP are disclosed. A tube pressing member is swingable in an axial direction of the drive shaft. The structural lines connected by one of the connecting portions and those connected by another one of the connecting portions are at least partly different from each other. vacation place, office, etc and at their convenience, irrespective of the distance the survivor is from the actual physical location of the remains, the time of day, and the weather.