The present invention relates to chalcone and chalcone derivatives and analogs which are useful as angiogenesis inhibitors. The invention further provides a silver halide emulsion prepared by the method, and a photographic element comprising a silver halide emulsion prepared by the method. By blocking blue light and ultraviolet light from reaching the retina, the IOL thereby prevents potential damage to the retina. The gate electrode may only partially deplete a region of the semiconductor body, and the partially depleted region may be used as a storage node for logic states.