Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein. A thermally conductive liner lines an interior of the outer shell. The liquid is directed through a conduit within the separator. The location determining element is configured to process a location signal to determine a current geolocation of the electronic device. The deflector plate is mounted on an arm for positioning the deflector plate between the ejection port on the receiver of the gun and the rail on the accessory mount.