Detergent compositions and, more specifically, low pH detergent compositions comprising nonionic surfactants that are suitable for washing of clothes, and methods of making and using the same. The apparatus includes a door and a sensor for detecting ozone in a space enclosed by the door. In addition, they may be used in screening and diagnosis assays for abnormal GENSET expression andor biological activity and for screening compounds that may be used in the treatment of GENSET-related disorders.