The present invention relates to a new class of compounds having \u03b3\u03b4 T cells activating properties referred to herein as angelyl or tiglyl phosphoesters, compositions comprising any of these compounds and methods for regulating an immune response in a subject comprising the step of administering these compounds. The lens actuating device has a power transmitting shaft connected to the lens holder for movement in axial directions thereof, and a fluid case having a shaft support sleeve and filled with a working fluid, the power transmitting shaft being axially slidably supported in the shaft support sleeve. Each of the N location indicators is configured to transmit a different location signal. Though the improved concealed carry clips have, to date, been designed for Clock\xae, M&P\xae and Springfield Armory\xae XD handguns, the concealed carry clips may be adapted for use on other similarly constructed handguns in the future. In these embodiments, the engaging structures may take several forms including threads, small posts, circular or semi-circular receiving members, andor a slot.