A method of determining the functional activity of the MRP2 andor MRP3 efflux pathway of a human or animal subject was disclosed. Therefore, a vehicle need only process certificates and certificate revocation lists for the particular region that it is traveling in. The fixing base is adapted to be fixed to a fixing object. Fibers of the non-woven are embedded in at least one of the lands and in the sidewalls of the discrete extended elements through the open proximal ends. When the problem is reproduced, these data are used to simulate the situation at the time of problem occurrence by using simulation unit. Embodiments of a container in which the side portion opposing the side support portion includes a receiving portion for receiving at least a portion of the support protrusion from a second similarly configured container are also disclosed.