Compounds of formula, where R is a monovalent cyclic organic group having from 3 to 15 atoms in the ring system, useful as pharmaceuticals. The forward osmosis membrane has a composite membrane structure including a nonwoven fabric layer, a hydrophilic polymer layer, and a polyamide layer. A gate electrode is patterned on the segmented active devices between the sourcedrain bridges such that it has a reduced length between the segments. The gain selection is processor controlled through the use of a digital look-up table stored with predetermined gain functions andor data that are both time and frequency specific. The oxide layer is exposed to a nitrogen-containing gas to nitridize the surface of the oxide layer and reduce the effective dielectric constant of the oxide layer.