Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure. The user interface is configured to receive a plurality of communications requesting location information for a plurality of mobile devices engaged in communication sessions with a communication network. The deduplicated data processing rate is regulated using a rate control mechanism. Furthermore, an ion current meter is coupled to the ion current collector to measure the ion current.