Compounds of formula :are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating atherosclerosis. A biosensor can be created by placing a reporter gene under control of an inducible promoter. The third step is to assign a numerical value to each of the criteria observed in step two. The method provides for very rapid detection of high-speed data stores. For each pixel, an included pattern recognition algorithm determines when the pixel represents the backing.