The invention relates to an alarm. A trench is formed in the substrate. The gaming machine also includes a light-guiding panel. Classification features are selected primarily from descriptors of the morphology of the individual calcifications and the distribution of the cluster as well as patient’s demographics as input to the network. Use of a composite density profile affords the system increased resistance to channel dynamics such as fading, birth and death, which reduces degradation due to mistiming caused by such channel dynamics. First and second sets of seeds are placed on the first voxels and a second set of seeds respectively.