The disclosure relates to methods of controlling the state of a virus in an individual, such as a method of reactivating a latent virus in an individual, comprising administering one or more agents that modulates the activity of signal transducer and activator of transcription 3 or any of p300, CBP or p300CBP. In the display region, the gate line and a data line cross to define a pixel region and a thin film transistor is disposed at the crossing portion of the gate and data lines. The phase compensation unit performs phase-shift in the compensation frequency band through a frequency shift process, instead of an increase in compensation gain. This includes using the decision and reliability information corresponding to the unpadded data and the decision and reliability information corresponding to the padded data, where a preference is given to the decision and reliability information corresponding to the padded data over the decision and reliability information corresponding to the padded data during message passing. The invention also extends to methods of making the said compounds.