Devices and methods for cooling all or part of the body of a human or animal subject by inserting a heat exchange catheter into the subject’s body and infusing into or through the catheter a heat exchange medium that contains liquid phase matter and frozen solid phase matter, wherein at least some of the solid phase matter melts while in the catheter. Harvested Web pages are examined for keywords to identify categories to which they pertain. 3, and with MgO-concentration of 5 to 13% by mass as to the slag composition, which are dependent upon the concentration of each of CaO, MgO, and SiO2, contained in the raw material mixture. Enzymes can be detected by binding to receptors comprising materials that bind to the active site of the enzyme. The present invention also relates to antibodies that bind specifically to a human ANK, and methods for producing human ANK polypeptides.