A first connector is fixed to a panel via a first bracket. An interconnect module is configured to be coupled to the base member. Methods of enhancing cellular uptake, modulating tissue distribution and enhancing pharmacological activity of RNase H-independent antisense oligonucleotides are also provided. A plurality of connecting members extend between and are connected to adjacent support members, with the connecting members having a height that is less than a height of the support members to which the connecting members are connected, and an upper surface that is substantially flush with an upper surface of the support members to which the connecting members are connected. A thermal anneal process for the top clad layer can be a temperature within a range of 950C to 1050C.