Disclosed herein are a CMOS image sensor and a method of manufacturing the same, which can reduce current leakage through a plug connecting a photodiode and a transfer transistor to each other, and thereby provide low dark current levels. NGAL is a small secreted polypeptide that is protease resistant and consequently readily detected in the urine following renal tubule cell injury. The coil offers a cat a lifelike chaotically varied motion and response to mimic a cat’s natural prey and evoke a cat’s natural hunting instincts. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV227310.