The invention is directed to multi-functional N-maleimidyl polymer derivatives comprising a water soluble and non-peptidic polymer backbone having a terminal carbon, such as a poly, the terminal carbon of the polymer backbone being directly bonded to the nitrogen atom of a N-maleimidyl moiety without a linking group therebetween. A synthetic communication server receives updated status of a target phone device referencing a normalized phone number that specifically identifies the target phone device on a synthetic communication network. The label includes information such as postage, delivery address, return address, and a barcode for tracking delivery information.