A method of product packaging wherein oblong sleeve-simulating product packaging labels are adapted to be printed with variable product information as weight data and are fed long-edge first towards a product packaging station while being maintain in an indexed relationship to a series of product items which are likewise fed towards the product packaging station. The invention shows a way of nevertheless using such preoperatively acquired images for superimposition with 2D projections of the soft parts, taking an indirect route via 3D3D registration of images of the spinal column. In this way, a more accurate representation of the performance of the system may be measured, detected, determined andor obtained. The stiffener can have a first attachment portion attached to the first face sheet, a second attachment portion attached to the second face sheet, and an intermediate portion extending between the first and second attachment portions. Such a composition can be administered to a subject for the treatment or control of bacterial conjunctivitis caused bay an antibiotic-resistant bacterium.