The invention provides compounds of formula I:wherein a, b, c, m, n, q, r, W, Z1, Ar1, Z2, Y, R1, R2, and R3 are as defined in the specification. The modulator, which applies a phase modulation to communication data, provides a storing circuit that stores inputted communication data of binary signals, a converting circuit that converts binary signals of 11 digits into ternary signals of 7 digits, and a multilevel modulator that generates modulation signals based on the ternary signals of 7 digits, and outputs modulated waves. The support portion has a vacuum aperture for communication with a source of vacuum, and a retention structure for releasably mounting within a hand piece of an intraductal fluid aspiration system. In another embodiment, external source provide information to the filtering system. An alternating electromagnetic field may be introduced to selectively induce localized heating of the interface structures. An array of probes according to the present invention may be employed as a system to dewater a volume of particulate.