The efficiency is improved for a lithography step in a process of manufacturing semiconductor integrated circuits. The methods employ a primary self-organizing map trained with biological marker profiles from tissues having known diseases or conditions, in combination with a secondary self-organizing map which displays a representation of a subset of the primary self-organizing map with sample data obtained from an individual in need of diagnosis. The present blends exhibit reduced color formation, a high level of whitenessbrightness and acceptably low haze formation upon heat treatment. Finally, a data processing subsystem first detects the spectral locations of peaks in the spectrum using the sample data and then uploads the peak information to a host computer before performing processing to determine the shapes of the peaks andor noise information for the optical signal, for example. In some embodiments, the wirebond between the differential outputs can be configured so that its contribution to mutual inductance is reduced or substantially nil. When the uncured rubber layer is formed on the film layer, at least one uncured rubber strip is applied serially onto the film layer to form the uncured rubber layer.