The present invention provides an automatic control system, method and paper manufacturing machine using such control system for automatically controlling the amount of press section dewatering via the metered application of chemical dewatering agents applied to a paper web in a paper manufacturing process. shoe upper stretching process 2. The stored information change is accessed with respect to a time. The first electrode terminal is a terminal of an external lead electrode, for example. In certain aspects, information from assessment of the presence, absence, andor direction of a tail effect in a metabolite distribution curve is utilized to predict risk of ASD andor to differentiate between ASD and DD.