The present invention provides a biosensor that enables highly-accurate measurement of a sample solution including a solid component like hemocytes and has a little variation in response. The reactor effluent stream is distilled to produce a dichlorohydrin-rich vapor phase effluent stream. The contoured portion includes contoured corner segments and contoured elongated segments extending between respective pairs of the contoured corner segments. The perimetric flange advantageously incorporates some lateral projections or centering stops of the facing lamina in order to optimise the pressing. At the encoded level, the user data are organized in a matrix structure comprising a first set of data sectors and are encoded, respectively, by means of the inner code in the horizontal direction of the matrix and by means of the outer code in the vertical direction of the matrix. In preferred embodiments the nucleoside analogs have either or -chirality at the 5\u2032-carbon.