Single nucleotide polymorphisms associated with serum C-reactive protein levels are disclosed. The apparatus collects both the specularly reflected light from the anterior surface of the cornea and diffusely reflected light from the interior of the cornea. The power devices are connected to the circuit baseplate through wire bondings. A numerical value obtained from iterative calculations is assigned to the subject wave pattern based on the comparison. With such measurement chair of simple constitution, a motion of upper part of the subject is effectively restricted without giving the sense of oppression to the subject and a living body optical measurement apparatus, which permits a living body optical measurement with high measurement accuracy is obtained.