1460717015-21280932-fc0c-4480-97d5-0b2e3f5e7abc

Novel bisamidate phosphonate prodrugs of FBPase inhibitors of the Formula IA: 1and their use in the treatment of diabetes and other conditions associated with elevated blood glucose. In this method, a lithiated compound to be coated and an organic solution or aqueous solution including a coating-element source are putted into a mixer, the mixture is continuously stirred to mix the contents thoroughly, and a hot dry gas is introduced into the mixer to evaporate the solvent while the powder is continuously agitated. The driving head is mounted beneath a hollow shelf, includes a driven shaft and a blade fixedly connected to the driven shaft. The use of two generally coplanar inflatable bladders arranged to provide an overlap between the two bladders, is preferred. Phosphor layers are formed within each of the discharge cells. A discontinuous interfacial material is included between the cell material and the ion-source material.