The invention provides crystal structure of the kinase domain of BTK, as well as use of the crystal structure in the design, identification, and verification of ligands that modulate BTK activity. A request is received from a user utilizing a local system. Such a device allows a user to connect the cellular phone to a data link connector located in a vehicle, download software to either an adaptor or the cellular phone, retrieve information relating to diagnostic tests on the vehicle and view the results on the cellular phone display, andor communicate the results to another person or device. Each golf ball receiving unit may include a heating element. The cutterhead can be rolled over the ground with the aid of the guide wheel.