A processing solution container package system includes a frame that supports the containers of the package system and allows each of the containers to collapse while avoiding a trapping of solution within the containers. Protein and variant levels can be determined using quantitative methods in which the proteinvariant signals are normalized to signals of internal reference standard species and the values compared to working curves constructed from samples containing known concentrations of the protein or variants. The second member has a lumen and a side opening in fluid communication with the second lumen, wherein at least a portion of the first member is positioned within the second lumen of the second member. The spray gun cartridge is removable from the manifold body without disconnection of fluid supply lines to the manifold body and without removal of the manifold body from a ganged mounted array of such spray modules. The signals are time division multiplexed across the common metal trace such that a single metal layer of an integrated circuit is used to multiplex signals to and from a poly-silicon layer, reducing utilization of upper metal layers of the integrated circuit.