The present invention provides a novel antagonist: N–5–2–3–2-oxopyrrolidin-1-yl)cyclohexyl)acetamide:or a pharmaceutically acceptable salt, solvate or prodrug, thereof, having unexpected dual CCR-2 and CCR-5 receptor activity. One or more linked plan models are identified in the network of plan models that are linked to the focus plan model, link expressions defining links between the plan models. The hydrated component has a melting point below about 100 C. The value-added service provider transmits the applicable rate for the use of the requested value-added service to the mobile telephone network operator in the form of a new destination number for the requested value-added service. When medical images have been displayed, the frequency-of-use storage unit stores the frequency of use of the layout type. The waveforms having been transmitted to a material interface of interest are divided into a number of time zones and the amplitudes of the waveforms within the time zones compared against waveform amplitudes obtained from known acceptable joined material interfaces to determine the quality of the material interface of interest.