Systems and methods conducive to the formation of one or more alkene hydrocarbons using a methane source and an oxidant in an oxidative coupling of methane reaction are provided. A dielectric layer Is formed that partially fills each of the trenches, covering the first and second sidewall portions. In one implementation, the memory controller includes a write data generation circuits to each transmit a data signal to the memory on a data line, the write data generation circuits being controlled by write enable signals. Methods of reducing or preventing loss of kidney function andor renal mass or volume, and methods of delaying progression to chronic kidney disease are also provided. A plurality of Load Management Modules is provided. The supply member includes first and second supply members in which liquid supply passages are provided and filters provided between the first supply member and the second supply member.