Methods for inhibiting angiogenesis in endothelial cells and selectively inducing apoptosis in endothelial cells via compounds which binds annexin II are provided. A second paper document is vacuum-secured below a second vacuum belt that extends from a second trailing roller to a second leading roller. The well layer contains indium and nitrogen, while the barrier layer contains aluminum and nitrogen. An annular collar is disposed concentrically about the male die and resiliently supported on the upper support plate such that, when the two plates are urged toward each other, the collar seals the upper and lower ends of the die space, and a volume of pastry dough disposed in the cavity of the female die is formed into a pastry shell conforming to the die space.