The present invention relates to improved processes for the production of 2-amino-2-2-ethylpropane-1,3-diols, and to compounds for use therein. The methods include matching the coefficient of thermal expansion of injection molding materials for the connectors and heat sinks. The lithium composite material comprises a core of lithium metal and a coating of a complex lithium salt that encapsulates the core. The replicon andor the produced virus may be used to prepare a vaccine, for instance for the prophylaxis of AIDS.