The invention provides isolated PR1-C10 nucleic acids and their encoded polypeptides. The gripping instrument has a first pair of coagulation sections with a first lower coagulation section on the lower jaw part and a first upper coagulation section on the upper jaw part and, further, a second pair of coagulation sections with a second lower coagulation section on the lower jaw part and a second upper coagulation section on the upper jaw part. Thus, no transaction in a group will be dependent upon any other transaction in the group. Based on detection values and conditional probabilities associated with the triggersmarkers, a probability estimate of a future arrhythmia is computed. The present invention is also directed to compositions containing lipophilic fluid, a polar phase and a bleach system.