The invention provides methods for the treatment of diseases and conditions mediated by increased phosphorylation, such as inflammation and cancer. Current collectors are provided on the positive electrode layer and the negative electrode layer, respectively, of the element body using a conductive material, such as Pt. The system continually updates the degree of likelihood of a match of a health care provider with an individual based upon individual feedback and clinical trial provider feedback relating to results achieved from treatment provided by a given health care provider.