A high-throughput laser desorptionionization mass spectrometer has been developed and is described herein. Methods of making and using the same are also provided. However, on-path support methods only address time-transfer errors introduced inside network elements and any asymmetry in the transmission medium, such as, for example, the fiber strands for the two directions of transmission, cannot be compensated for by on-path support mechanisms. The voltage detection unit connects with a logic signal switch. The pixel portions are disposed in the display area and electrically connected to the gate and data lines. A variety of Met kinase inhibitors may be used in conjunction with tocotrienols in the treatment or prevention of cancer.