A non-invasive optical sensor which uses the motion signal to calculate the physiological characteristic being measured. The input pin may be multiplexed so that the appropriate input signal is directed to appropriate circuitry within the controller to support two or more functions of the controller. Also, since the weakened region 18 having a predetermined depth is formed on the rear face 21 of the object 1 along the line to cut 5, the object 1 can be cut along the line to cut 5 with a relatively small external force. A self-assembly monolayer is positioned on the reference electrode. Methods have also been developed to predict populations at risk, based on the role of cholesterol in production of A. Thereafter, the adhesive material is at least partially cured to adhere the material to the attachment surface to form an assembly and the assembly is assembled to an article of manufacture.