Disclosed are embodiments a software architecture for benefits management. An adenovirus expression vector includes the Smad4 or Smad3 gene. Also, preferably, the enlarged string holes are defined by a pair of opposed interior walls of the frame extending between the frame’s inner and outer surfaces, thereby forming a truss-like internal structure for stiffening the frame. The compositions impart protection to the treated wood products, especially damage caused by exposure to water and insects.