A method for regenerating pancreatic tissue using recombinant periostin protein, a nucleic acid encoding said periostin and pharmaceutical compositions comprising said periostin are disclosed. A first plurality of the amplification paths include series-connected pluralities of the amplifiers and share a common first series-connected amplifier, and a second plurality of the amplification paths have different first amplifiers. The first sensor is configured for measuring at least one of force, torque, and distance feedback.