The chip resistor 10 includes a ceramic substrate 11 that is shaped like a rectangular parallelepiped. The transition member is positioned between a rigid member and a flexible member, which are each adjacent to the flexible element. , a DPP-IV inhibitor, in the treatment of a proliferative disease. The tapered hub includes at least one inner ring configured to abut against the at least one recess or finger while the surgical instrument is inserted into the cannula of the surgical access port. Preferably, the first low-elasticity area applies a force that raises the side of the fifth toe toward the ankle curve portion thereby providing a resistive force against the ankle twisting inwards.