An embodiment relates to a selective agonist of neuronal nicotinic acetylcholine receptor \u03b17 subtype, a pharmaceutically suitable salt, prodrug, or a metabolite thereof, for the prevention and treatment of diseases and conditions that are mediated by nicotinic acetylcholine receptors, and methods of use thereof. The method includes estimating a channel using a signal received over one or more receiver antennas; generating one or more weights using the estimated channel to cancel interference; detecting a candidate symbol having the shortest Euclidean distance through Maximum Likelihood using a first weight; and soft-decoding the candidate symbol using a second weight. The wheel may also include a brake mechanism. In addition, a path table whose contents are commonly generated by network analysis procedures contains rows which describe corresponding paths each consisting of an alternating sequence of nodes and links. The X-ray tube and the X-ray detector are installed on the second arm.