Among other things, embodiments of devices are disclosed that can be used in treating Barrett’s esophagus. According to an important aspect of the invention, at least two elongate flow passages are arranged in parallel between the first adsorbent chamber and the second adsorbent chamber. Neither the position indicators nor the tools are limited to particular positions or orientations such as by a repeating or incremental support structure on the flat sheet. An elongated, flexible, non-stretch ankle belt is secured to the body member proximate its upper end, and is adapted for extending circumferentially around a lower leg of the wearer. The mounting assembly may further include a deflection adjustment member engaging the attachment member and a fixed support member to provide variable control of roller tube deflection. A wash-free delivery system introduces reagent into at least one reaction containment device without requiring washing of delivery components.