Described herein are methods of detecting an infection and for detecting the presence or absence of microorganisms, for example, wound pathogens in a sample, by contacting a sample with an enzyme produced andor secreted by the bacteria, and detecting modification or the absence of modification or the substrate, as an indicator of the presence or absence of the enzyme in the sample. The machine includes a housing, a card reader in operatively-supported connection with the housing and operative to read indicia on user cards corresponding to financial accounts, a display in operatively-supported connection with the housing, and a cash dispenser in operatively-supported connection with the housing. Wing ends can be curved discs for stability. More preferably, the control unit causes the display unit to display the plurality of candidate traveling routes, each with the traveling mode overlaid thereon, and selects in response to an instruction of the operator one traveling route planned to be taken among the plurality of candidate traveling routes.