The main difference between the boost bridge amplifier according to this invention and state of the art class D amplifiers is in the connection of a load between a power supply and a switching bridge which is supplied from a bridge capacitor. The accumulated value has a positive saturation value of +4 and a negative saturation value of 4. The invention further relates to methods for producing the lettuce cultivar, represented by lettuce variety 79-459 RZ. The other side of the diffuser plate can be a plane or having a lens structure. The invention further relates to diagnostic and therapeutic methods useful for diagnosing, treating, preventing andor prognosing disorders related to these novel polypeptides.