A valve timing control device according to the present invention has a between-sealing-faces clearance defined between a frontal end of each shoe of a first rotor and an outer periphery of a boss section of a second rotor corresponding to the frontal end of the shoe and accepting the quantity of oil leaks having no effect on the responsibility of the device as a maximum value. A reception module receives from a base station a Reverse-Link Assignment Message including a Packet Format field and a Reverse-Link Power Control field. Also provided by the invention are rAAV vector-based compositions, virus particles, host cells, and pharmaceutical formulations that comprise them useful in the expression of selected therapeutic proteins, polypeptides, peptides, antisense oligonucleotides andor ribozymes in selected mammals, including organs, tissues, and human host cells. Methods for treating viral infections, including Hepatitis C viral infections are provided by the disclosure. The DAC includes a first charge pump adapted to produce the first charge and a second charge pump adapted to produce the second charge.