Epothilone resistant cells lines are disclosed. One or more drives control motors driving the movements of the manipulator. A filter for an infrared imaging system has detectors sensitive to radiation in an infrared transmission spectrum. This prevents the braking mechanism from being activated prematurely and leaves sufficient time to deactivate the braking mechanism after the wrapping operation. The analgesic \u03b1-adrenergic receptor can be, for example, the \u03b1-2B receptor. An approach for facilitating the application of a clutch when it is not a simple onoff mechanism provides an enhanced interface for the conversion between hydraulic energy and mechanical energy, thereby improving efficiency within the hydraulic drive system.