The present invention relates to an end closure member with at least one feed-through, whereby the end closure member has at least one through-going feed-through opening and whereby the through-going feed-through opening cross-section varies along the end closure member in a longitudinal direction. To find the exact match or the best matching prefix, patterns have to be compared a bit at a time until the exact or first: match is found. The invention additionally provides a process for the evaporative concentration of solutions in an evaporator having a self-cleaning microstructured heat exchange surface, the solution for evaporative concentration preferably comprising viscous or solid constituents in solution, emulsion or suspension. The livestock feeder is suitable for providing feedstuffs such as nutritional supplements to a livestock animal on a free-choice basis. In the method, a therapeutically effective amount of a selective muscarinic m1 agonist compound is administered to a patient in need of such treatment. Each blade includes a straight first outer portion, a straight second outer portion, and a third middle portion joining the first outer portion to the second outer portion.