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A tool, such as a multipurpose tool, is provided that is designed to receive a separate tool member configured to be installed after assembly of the tool. The SLC34A2-ROS fusion proteins are anticipated to drive the proliferation and survival of cancer cells, and particularly drive the proliferation and survival of a subgroup of NSCLC tumor cells. The sensor may optimally have a dielectric coating. Mice vaccinated with rNcCyP, rNcSRS2, or the combination of rNcCyP and rNcSRS2 responded with high levels of NcCyP- or NcSRS2- specific antibodies. Light transmittance is modulated by the electric field generated by the electrode structures changing the birefringence index of the liquid crystal composition layer. When the element moves below a predetermined limiting value, a relatively great switching hysteresis is set, and when the limiting value is exceeded, a reduced switching hysteresis is set.