The present invention provides a method of treatment of thrombotic thrombocytopenic purpura and hemolytic uremic syndrome with protein C. The multiple channels of information may be comprised and encompass spatial, angle, spectral and polarization domains. Light from a light source is received at the digital micromirror device. 7 times greater than the width of each groove or turn. In one aspect of the invention, porcine pancreatic primordia are implanted into a mammalian subject, and after a period of time sufficient to induce tolerance, porcine islet cells are implanted in the subject. Generally, the desired composite noise figure profile is produced, while attempting to minimize the deviation of the composite gain profile from the desired composite gain profile.