A locator or signaling device and a detector system for locating lost dentures includes a button or insert that can be mounted on the surface of an existing denture. In one embodiment, a radio network controller initiates an inter-Node-B soft handover. If the total number of comparison errors does not exceed a tolerance threshold that is greater than zero then the frame is aligned. Depressions are machined in the machine direction center of the sealing bars in order to accommodate the shape of the fitment. The enzyme electrode of the invention can provide high response current values.