A damascene structure and method of making the same in a low k dielectric material employs an imageable layer in which the damascene pattern is provided. Furthermore, a corresponding measuring method is proposed. The prior art separates the two memory units in different areas on a chip so that the circuit layout is not optimized. This invention further provides a Single Nucleotide Polymorphism -based DNA fingerprining method for rapid and accurate genotyping, identification as well as DNA analyses of genetic data from human beings and different organisms.