A concentrated esmolol formulation is provided that is distinguishable from a diluted form of the concentrated esmolol formulation. An auditory-event-responsive audio upmixer or upmixing method is also disclosed. The rake arms are attached to a rake arm pivot, and can be extendable to a horizontal working position and retractable to a transport position. Such fraction are obtained with a method such as by a fruit juice or squeeze being absorbed onto a synthetic resin adsorbent and the adsorbed components being eluted by a solvent, or by extracting fruit juice or squeeze with ethanol.